Alprostadil - Caverject
Caverject is drug for treating impotence. The initial dose of Alprostadil is usually around 1.25 mcg to 2.5 mcg with dose increases depending on response until the effective dose is reached. The maximum daily dose should not exceed 60 mcg. Alprostadil belongs to a class of medications known as prostaglandins. Prostaglandins like alprostadil cause increased blood flow to certain areas of the body... Caverject is drug for treating impotence. The initial dose of Alprostadil is us...
Alprostadil is used to treat male impotence. Your doctor also may use Alprostadil to help diagnose the exact nature of your impotence. Caverject is taken by injection.
Alprostadil is injected into a specific area of the penis and produces an erection within 5 to 20 minutes. Do not use Alprostadil more than 3 times a week. Wait at least 24 hours between use.
The first injections are performed by your doctor in the doctor's office in order to determine the proper dosage. Afterward, you can inject Caverject yourself as needed. Your doctor will train you in the proper technique for injecting Alprostadil and you'll be given complete printed instructions. Follow these directions exactly and do not change the dose your doctor has determined.
Do not use a Caverject solution that appears cloudy or colored or that contains particles. Do not shake the vial.
Wash your hands thoroughly and do not touch the needle. Carefully choose the injection site as instructed by your doctor, always avoiding visible veins. Cleanse the site with an alcohol swab. With each use, alternate the side of the penis and the site of the injection.
Use the needle/syringe and vial only once, then discard them properly. Do not share needles or allow anyone else to use your medication.
Caverject comes in both 10 micrograms and 20 micrograms strengths. Make sure you are using a vial with the correct strength.
Once the Caverject solution is mixed, you must use it immediately or discard it.
Newborns - IV 0.01 to 0.4 mcg/kg/min. Drug is infused for shortest time and at lowest effective dose.
Impotence (Erectile Dysfunction of Vasculogenic, Psychogenic, or Mixed Etiology)
Intracavernosal Initiate dose titration at 2.5 mcg. If there is a partial response, the dose may be increased by 2.5 mcg to a dose of 5 mcg and then in increments of 5 to 10 mcg, depending on erectile response, until the dose that produces an erection suitable for intercourse and not exceeding a duration of 1 h is reached. If there is no response to the initial 2.5 mcg dose, the second dose may be increased to 7.5 mcg, followed by increments of 5 to 10 mcg. If there is no response, then the next higher dose may be given within 1 h. If there is a response, then there should be a 1-day interval before the next dose is given.
Erectile Dysfunction of Pure Neurogenic Etiology (Spinal Cord Injury)
Initiate dosage titration at 1.25 mcg. The dose may be increased by 1.25 mcg to a dose of 2.5 mcg, followed by an increment of 2.5 mcg to a dose of 5 mcg, and then in 5 mcg increments until the dose that produces an erection suitable for intercourse and not exceeding a duration of 1 h is reached. If there is no response, then the next higher dose may be given within 1 h. If there is a response, then there should be at least 1-day interval before the next dose is given.
Storage - To store Caverject:
- Store unused packs of Alprostadil at room temperature for up to 3 months. Protect from freezing or from overheating.
- When traveling, take care to prevent exposing Caverject to freezing or excessive heat. Do not store Caverject in checked luggage or leave it in a closed car.
Caverject Side effects:
Side effects cannot be anticipated. If any develop or change in intensity, inform your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue using Caverject.
The most common side effect is mild to moderate pain in the penis during and/or after injection, reported by about one-third of users. A small amount of bleeding may occur at the injection site. Notify your doctor if you have a condition or are taking a medication that interferes with blood clotting. As with any injection, the site can become infected. Call your doctor if you notice any redness, lumps, swelling, tenderness, or curving of the erect penis.
Your doctor should examine your penis regularly if you use Caverject. Use of Caverject may result in formation of fibrous (hardened) tissue in the penis or erections at an unusual angle. If those side effects occur, inform your doctor and stop using Caverject.
More common side effects may include:
Blood-filled swelling at the site of injection, disorder of the penis (such as discoloration of the head, strange feeling, tearing of the skin), hardened tissue in the penis, pain in the penis, prolonged erection, upper respiratory infection.